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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

Question 1

A clinical microbiology laboratory is using a nucleic acid amplification test (NAAT) to detect Mycobacterium tuberculosis directly from sputum. A positive result indicates:

A. The presence of M. tuberculosis DNA, which could be from viable or non-viable organisms.
B. Active tuberculosis disease requiring immediate treatment.
C. The presence of viable M. tuberculosis organisms.
D. Drug susceptibility information for the M. tuberculosis strain.

Question 2

A patient presents with a pruritic rash consisting of raised, serpiginous tracks on their skin. The patient recently returned from a Caribbean vacation and reported walking barefoot on the beach. The MOST likely causative organism is:

A. Larvae of Ancylostoma braziliense
B. Sarcoptes scabiei
C. Pediculus humanus
D. Larvae of Strongyloides stercoralis

Question 3

A patient develops a severe skin and soft tissue infection following a boating accident in the Gulf Coast.
Wound cultures grow a Gram-negative, halophilic bacterium that is oxidase-positive. The MOST likely organism is:

A. Shewanella putrefaciens
B. Aeromonas hydrophila
C. Vibrio vulnificus
D. Pseudomonas aeruginosa

Question 4

A patient with a history of inflammatory bowel disease is diagnosed with primary sclerosing cholangitis and undergoes liver transplantation. Post-transplant, they develop a bloodstream infection with a Gram-negative bacterium that is identified as Fusobacterium nucleatum. This organism's role in the pathogenesis of colorectal cancer is primarily attributed to its ability to:

A. Modulate the host immune response and promote a pro-inflammatory microenvironment.
B. Form biofilms that physically obstruct the bile ducts.
C. Directly induce mutations in colonic epithelial cells.
D. Produce potent exotoxins that damage the intestinal epithelium.

Question 5

A patient presents with symptoms suggestive of primary syphilis. Which diagnostic test typically becomes positive earliest in the course of infection?

A. Treponema pallidum particle agglutination (TP-PA)
B. Rapid Plasma Reagin (RPR)
C. Venereal Disease Research Laboratory (VDRL) test on CSF
D. Darkfield microscopy of lesion exudate

Solutions: